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Dont fall In Love Marathi Poem प्रेम कुणावरही करू नये mahatransco amravati, mahatransco job, mahatransco operator recruitment nagpur, mahatransco recruitment, 

Syllabus for GPAT 2013 - 2014 Examination

Syllabus for GPAT-2013 Examination

Revised Syllabus of GPAT 2013 Examination

Get revised syllabus of GPAT 2013 Examination Click Here.

Previous year Graduate Pharmacy Aptitude Test Question papers

1. GPAT GATE 2003 question paper
2. GPAT GATE 2005 question paper

Graduate Pharmacy Aptitude Test 2013 Syllabus
Natural Products :
GPAT Pharmacognosy & Phytochemistry - Chemistry, tests, isolation, characterization and estimation of phytopharmaceuticals belonging to the group of Alkaloids, Glycosides, Terpenoids, Ster oids, Bioflavanoids, Purines, Guggul lipids. Pharmacognosy of crude drugs that contain the above constituents. Standardization of raw materials and herbal products. WHO guidelines. Quantitative microscopy including modern techniques used for evaluation. Biotechnological principles and techniques for plant development, Tissue culture.

GPAT Pharmacology :
General pharmacological principles including Toxicology. Drug interaction. Pharmacology of drugs acting on Central nervous system, Cardiovascular system, Autonomic nervous system, Gastro intestinal system and Respiratory system. Pharmacology of Autocoids, Hormones, Hormone antagonists, chemotherapeutic agents including anticancer drugs. Bioassays, Immuno Pharmacology. Drugs acting on the blood & blood forming organs. Drugs acting on the renal system.

GPAT Medicinal Chemistry :
Structure, nomenclature, classification, synthesis, SAR and metabolism of the following category of drugs, which are official in Indian Pharmacopoeia and British Pharmacopoeia. Introduction to drug design. Stereochemistry of drug molecules. Hypnotics and Sedatives, Analgesics, NSAIDS, Neuroleptics, Antidepressants, Anxiolytics, Anticonvulsants, Antihistaminics, Local Anaesthetics, Cardio Vascular drugs - Antianginal agents Vasodilators, Adrenergic & Cholinergic drugs, Cardiotonic agents, Diuretics, Anti-hypertensive drugs, Hypoglycemic agents, Antilipedmic agents, Coagulants, Anticoagulants, Antiplatelet agents. Chemotherapeutic agents - Antibiotics, Antibacterials, Sulphadrugs. Antiprotozoal drugs, Antiviral, Antitubercular, Antimalarial, Anticancer, Antiamoebic drugs. Diagnostic agents. Preparation and storage and uses of official Radiopharmaceuticals, Vitamins and Hormones. Eicosanoids and their application.


GPAT Pharmaceutics :
Development, manufacturing standards Q.C. limits, labeling, as per the pharmacopoeial requirements. Storage of different dosage forms and new drug delivery systems. Biopharmaceutics and Pharmacokinetics and their importance in formulation. Formulation and preparation of cosmetics - lipstick, shampoo, creams, nail preparations and dentifrices. Pharmaceutical calculations.

GPAT Pharmaceutical Jurisprudence :
Drugs and cosmetics Act and rules with respect to manufacture, sales and storage. Pharmacy Act. Pharmaceutical ethics.

GPAT Pharmaceutical Analysis :
Principles, instrumentation and applications of the following: Absorption spectroscopy (UV, visible & IR). Fluorimetry, Flame photometry, Potentiometry. Conductometry and Polarography. Pharmacopoeial assays. Principles of NMR, ESR, Mass spectroscopy. X-ray diffraction analysis and different chromatographic methods.

GPAT Biochemistry :
Biochemical role of hormones, Vitamins, Enzymes, Nucleic acids, Bioenergetics. General principles of immunology. Immunological. Metabolism of carbohydrate, lipids, proteins. Methods to determine, kidney & liver function. Lipid profiles.

GPAT Microbiology :
Principles and methods of microbiological assays of the Pharmacopoeia. Methods of preparation of official sera and vaccines. Serological and diagnostics tests. Applications of microorganisms in Bio Conversions and in Pharmaceuticalindustry.

GPAT Clinical Pharmacy :
Therapeutic Drug Monitoring Dosage regimen in Pregnancy and Lactation, Pediatrics and Geriatrics. Renal and hepatic impairment. Drug - Drug interactions and Drug - food interactions, Adverse Drug reactions. Medication History, interview and Patient counseling.

Latest News about M pharmacy Entrance Examination Notice

M. Pharmacy MH CET Notification

Come on National Hero's उठा राष्ट्रवीर हो

Come on National Hero's Marathi Poem

उठा राष्ट्रवीर हो
सज्ज व्हा उठा चला, सशस्त्र व्हा उठा चला

युद्ध आज पेटले, जवान चालले पुढे
मिळून सवर् शत्रूला क्षणात चारुया खडे
एकसंघ होऊनी लढू चला, लढू चला
उठा राष्ट्रवीर हो ...

वायूपुत्र होऊनी धरु मुठीत भास्करा
होऊनी अगस्ती ही पिऊन टाकू सागरा
रामकृष्ण होऊया, समर्थ होऊ या चला
उठा राष्ट्रवीर हो ...

चंद्रगुप्त वीर तो फिरुन आज आठवू
शुरता शिवाजीची नसानसात साठवू
दिव्य ही परंपरा अखंड चालवू चला
उठा राष्ट्रवीर हो ...

यज्ञकुंड पेटले प्रचंड हे सभोवती
दुष्ट शत्रू मारुनी, तयात देऊ आहुती
देवभूमी ही अजिंक्य, दाखवू जगा चला
उठा राष्ट्रवीर हो
Come on National Hero's is marathi poem where the writer appeals to his soldier, Said come on Soldirs keep moving on with your arms, today war is begun, with all we will dfeat our enemy. come on national hero's.

Maharashtra Sate Board SSC and HSC Results 2011

S.S.C. Result 2011

Welcome friends, The Results of SSC will declared on JUN 2011 at 12:00 P.M. You can see your SSC Maharashtra board result 2011 online here To check your HSC result online copy paste the url in your adress bar, Check your result here,
Put your seat No in Capital letter,
http://www.msbshse.ac.in/rh2011/
http://results.maharashtraeducation.net

SSC REsults 2011

वैसे लड़का हीरा है हीरा Famous Dialogue from Movie Sholey

Famous Dialogue from Movie Sholey

अब क्या बताएं मौसी !! वैसे लड़का हीरा है हीरा ! कमाने का क्या है अब आदमी जुए में रोज़ रोज़ तो जीत नहीं सकता है, कभी हांर भी जाता है| लेकीन लड़के की कीसमत बहुत अच्छी है| कभी कुछ बुरा नहीं कहता है| हाँ लेकीन दारू ऐसी चीज़ है की 1 बार अन्दर गयी तो फीर अच्छे बुरे का कहाँ धयान रहता है| वैसे ये ज्यादा दारू भी नहीं पीता लेकीन जब भी वो नाचने वाली के पास जाता है तो पता नहीं इसे क्या हो जाता है...पीता ही चला जाता है, कनट्रोल ही नहीं कर पाता है! मैं तो कहता हूँ की रीशते के लीए इससे अच्छा लड़का मिळना मुश्कील है| हाँ बस घर का ठीकाना नही है| उसका क्या है आज नहीं तो कल वो भी हो जायेगा| लेकीन लड़का हीरा है हीरा |

चांदीच्या ताटात ठेवले होते गहू The Marathi Wedding Quote Ukhane

Marathi Ukhane

चांदीच्या ताटात ठेवले होते गहू
लग्नच झाले नाही तर नाव कसे घेऊ

एक होती चिऊ एक होती काऊ
गणपत रावांच नाव घेते , डोक नका खाऊ

अंगणात पेरले पोतेभर गहू
लिस्ट आहे मोठी, कुणा-कुणाचे नाव घेऊ

चांदीच्या ताटात जिलेबीचे तुकडे
घास भरवते मरतुकड्या, थोबाड कर इकडे

बागेमध्ये असतात, गुलाबांच्या कळ्या
गणपतरावांचे दात म्हणजे दुकानाच्या फ़ळ्या

वाकडी तिकडी बाभूळ, तिच्यावर बसला होला
सखा पाटील मेला , म्हणून तुका पाटील केला

लग्नाच्या पंक्तीत घेतला उखाणा खास
अन गणपतरावांच्या घशात अडकला घास

आजघर माजघर माजघराला नाही दार
गणपतरावांच्या घरात मात्र विंडोज दोन हजार

कर्दळीच्या वनात चंडोल पक्षी लपला
XXX शी लग्न करून YYY जन्माचा धुपला

कंप्युटरला असते फ़्लॉपी डिस्क
हिच्याशी लग्न करून मी घेतलिय मोठी रिस्क

रेशमी सदर्‍याला प्लास्टीकचे बक्कल
गणपतरावांना आहे टक्कल, पण डोक्यात नाही अक्कल

समुद्रच्या काठावर मऊ मऊ वाळू
गणपतराव दिसतात साधे, पण आतून एकदम चालू

keep in visiting for more marathi content.

MPSC Rajya Seva Examination 2010 Answer Keys

Answer Keys of MPSC Rajya Seva Examination 2010

All the Answer keys of MPSC Rajya Seva Examination Based on refrance books & my own knowladge.
The right answer highlited in Bold. 
 MPSC Rajya Seva Examination Quetion Booklet  D
1. How dose Reserve bank of India Controle the credit money?
a) Bank rate   b) Change in Cash reserve ratio
c) Open market Operations  d) All the Above

2. १९५८ साली भारतरत्न हा किताब मिलावानारे महाराष्ट्रातील समाज सुधारक कोण?

a) Dr. Babasaheb Ambedkar   b) Dr. Panjabrao Deshmukh
c) Dhondo Keshav Karve  d) Mukundrao Patil

3. Some birds are animals, all sky is animal then which of the following sentence is correct?

a) Some sky is bird  b) All animals are birds
c) Some animals are sky  d) Some Birds are sky

4. D is right option


5. Which five year plan for the first time had declared the objective to combat inflationary pressure?

a) 1st    b) 2 nd
c) 7 th  d) 9 th

6. Who established the Industrial Association of Western India?
a) M G Rande  b) G G Agarkar
c) Dr. Panjabrao Deshmuk  d) Mukundrao Patil

7. Complete the following Series 4,3,12,9,36,81,?

a) 72    b) 108

c) 64  d) 124

8. स्वराज्य स्वदेशी बहिष्कार व राष्ट्रीय शिक्षण या चतु:सुत्रिचे पुर्स्कारते कोण होते?

a) Subhash Chandra Bose   b) Mahatma Gandhi

c) G K Gokhale  d) Lokmanya Tilak

9. In Maharashtra the area suitable for brackish water fishing is -------- lakh / ha
a) 0.19    b) 0.50

c) 0.75  d) 0.90

10. What was the original Surname of Dr. Panjabrao Deshmukh ?
a) Deshmukh   b) Kadam

c) Patil d) Mahajan

11. Answer is 3 rd Both the conclusions are logically correct

12. What is the tital of eleventh five year plan?

a) Human Development    b) Social justice & equality with development

c) Towrdas faster & more inclusive growth  d) None of this

13 When did India declared New Economic Policy?

a) June 1990    b) June 1991
c) June 1992  d) June 1993

14. Shantiswarup Bhatnagar award is given for the contribution in which field ?

a) Social service   b) Academic excellence
c) Scientific Research  d) Literature

15. Right option is 3rd P

MPSC answer keys 2010

Keep in touch for more answers.

Graduate Pharmacy Aptitude Test [GPAT] 2010 Answer Keys | GPAT 2010 Question Paper

Graduate Pharmacy Aptitude Test [GPAT] 2010 Answer Keys

• GPAT question paper contains 100 questions.
• Each question has 4 choice for its answers ABCD 
• Only one of them is the correct answer.
• For each correct answer, you will awarded 3 marks.
• For each wrong answer, you will awarded -1 marks.

GPAT 2010 Question Paper

Q.l The vitamin essential in tissue culture medium is
(A) Pyridoxine
(B) Thiamine
(C) Nicotinic acid
(D) Inositol
Ans. B

Q.2 Gingkgo biloba is used for its
(A) Expectorant activity (B) Lipid lowering activity
(C) PAF antagonistic activity (D)Antidepressant activity
Ans. C

Q.3 The amount of barbaloin present in Aloe vera is
(A) 1%  (B) 3.5-4%  (c) 1-1.5%  (D) 2-2.5%
Ans. B

Q.4 Sildenafil is used for treatment of one of the following disorders :
(A) Systolic hypertension (B) Unstable angina
(C) Pulmonary hypertension (D) Hypertension due to eclampsia
Ans. C

Q.5 Cardiac glycosides have the following configuration in the aglycone part of the steroid nucleus :
(A) 5a, 1 4 a - (B) 5a, 14β- (C) 5β, 1 4 a - (D) 5β,14β-
Ans. D

Q.6 Quassia wood is adulterated with
(A) Brucea antidysentrica (B) Cassia angustifoila
C) Cinnamomum zeylanicum (D) Cephaelis ipecacuanaha
Ans. B

Q.7 Eugenol is present in
(A) Fennel (B) Tulsi (C) Cardamom (D) Coriander
Ans. B

Q.8 Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive
patients with Chronic myeloid Leukemia?
(A) Pentostatin (B) Methotrexate
(C) Imatinib (D) L-Asparaginase
Ans. C

Q.9 Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin's
Lymphoma?
(A) Infliximab (B) Abciximab (C) Gemtuzumab (D) Rituximab

Q.10 Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum :
(A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine
Ans. B

Q.ll Which one of the following drugs does NOT act through G-Protein coupled receptors?
(A) Epinephrine (B) Insulin (C) Dopamine (D) TSH
Ans. B

Q.12 Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother
to the foetus?
(A) Lamivudine (B) Zidovudine (C) Indinavir (D) Ribavirin
Ans. B

Q.13 Improvement of memory in Alzheimer's disease is brought about by drugs which increase transmission in
(A) cholinergic receptors (B) dopaminergic receptors
(C) GABAergic receptors (D) adrenergic receptors
Ans. A

Q.14 Which of the following non-opioid analgesics is a prodrug?
(A) Piroxicam (B) Celecoxib (C)Nabumetone (D) Ketorolac
Ans. C


Q.15 Which one of the following drugs is NOT a typical anti-psychotic agent?
(A) Chlorpromazine (B) Haloperidol
(C) Risperidone (D) Flupentixol
Ans. C

Q.16 Which one of the followings is a plasminogen activator?
(A) Tranexamic acid (B) Streptokinase
(C) Aminocaproic acid (D) None of the above
Ans. B

Q.17 Myasthenia gravis is diagnosed with improved neuromuscular function by using
(A) Donepezil (B) Edrophonium (C) Atropine (D) Pancuronium
Ans. B

Q.18 Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?
(A) Daclizumab (B) Prednisone (C) Sirolimus (D) Tacrolimus
Ans. D

Q.19 The chemical behaviour of morphine alkaloid is
(A) acidic (B)Basic (C) neutral (D) amphoteric
Ans. B

Q.20 At physiological pH the following compound would be MOSTLY in the
(A) cationic form (B) unionized form
(C)zwitterionic form (D) anionic form

Q.21 Which one of the followings is used as a mood stabilizer for bipolar disorder and also in certain epileptic convulsions?
(A) Phenytoin (B) Lithium
(C) Sodium valproate (D) Fluoxetine
Ans. B

Q.22 An isosteric replacement for carboxylic acid group is
(A) pyrrole (B) isoxazole (C) phenol (D) tetrazole
Ans.-D

Q.23 The given antibiotic is an example of ansamycins :
(A) Roxythromycin (B) Adriamycin (C) Aureomycin (D) Rifamycin
Ans. D

Q.24 For glyburide, all of the following metabolic reactions are logical EXCEPT
(A) O-demethylation (B) aromatic oxidation
(C) benzylic hydroxylation (D) amide hydrolysis
Ans. B

Q.25 The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been attributed to its catabolism to dopamine. Carbidopa, can markedly increase the proportion of levodopa that crosses the blood-brain barrier by
(A) increasing penetration of levodopa through BBB by complexation with it
(B) decreasing peripheral metabolism of levodopa
(C) decreasing metabolism of levodopa in the CNS
(D) decreasing clearance of levodopa from the CNS
Ans. B

Q.26 Ethambutol molecule has
(A) two chiral centers and 3 stereoisomers
( B) two chiral centers and 4 stereoisomers
(C) two chiral centers and 2 stereoisomers
(D) one chiral center and 2 stereoisomers
Ans. B

Q.27 A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on
(A) Polarizability (B) Dielectric constant
(C) Dipole moment (D) Refractivity
Ans. C

Q.28 X-ray crystallographic analysis of an optically active compound determines its
(A) Optical rotatory dispersive power (B) Absolute configuration
(C) Relative configuration (D) Optical purity

Q.29 Which one of the following statements is WRONG?
(A) A singlet or triplet state may result when one of the electrons from the HOMO is
excited to higher energy levels
(B) In an excited singlet state, the spin of the electron in the higher energy orbital is
paired with the electron in the ground state orbital
(C) Triplet excited state is more stable than the singlet excited state
(D) When the electron from the singlet excited state returns to ground state, the molecule always shows
fluorescence phenomenon
Ans. C

Q.30 Aminotransferases usually require the following for their activity :
(A) Niacinamide (B)Vitamin B12
(C) Pyridoxal phosphate (D) Thiamine
Ans. C

Q.31 Purity of water can be assessed by determining one of its following properties instrumentally :
(A) pH (B) Refractivity (C) Viscosity (D) Conductivity
Ans. D
Q.32 Which one of the following statements is WRONG?
(A) Carbon NMR is less sensitive than proton NMR
(B) 12C nucleus is not magnetically active
(C) Both 13C and *H have same spin quantum numbers
(D) The gyromagnetic ratio of *H is lesser than that of1 C
Ans.D

Q.33 In the TCA cycle, at which of the following enzyme-catalyzed steps, incorporation of elements of water into an intermediate of the cycle takes place :
(A) Citrate synthase (B) Aconitase
(C) Maleate dehydrogenase (D) Succinyl Co-A synthase
Ans. C

Q.34 Humectants added in cosmetic preparations generally act by
(A) hydrogen bond formation (B) covalent bond formation
(C) complex formation (D) the action of London forces
Ans. A

Q.35 In the mixing of thymol and menthol the following type of incompatibility occurs :
(A) Chemical incompatibility (B) Therapeutic incompatibility
(C) Physical incompatibility (D) Tolerance incompatibility
Ans. C

Q.36 Bloom strength is used to check the quality of
(A) Lactose (B) Ampoules
(C) Hardness of tablets (D)Gelatin
Ans. D

Q.37 The characteristic of non-linear pharmacokinetics include :
(A) Area under the curve is proportional to the dose
(B) Elimination half-life remains constant,
(C) Area under the curve is not proportional to the dose
(D) Amount of drug excreted through remains constant
Ans. C

Q.38 In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is
(A) Schedule M (B) Schedule C (C) Schedule Y (D) Schedule H
Ans. A

Q.39 Thioglycolic acid-like compounds have applications in following type of cosmetic
formulations :
(A) Depilatory preparations (B) Epilatory preparations
(C) Vanishing creams (D) Skin tan preparations
Ans. A

Q.40 Which one of the following is a flocculating agent for a negatively charged drug?
(A) Aluminium chloride (B) Bentonite
(C) Tragacanth (D) Sodium biphosphate

Q.41 The healing agent used in hand creams is
(A) soft paraffin (B) urea
(C) bees wax (D) stearyl alcohol
Ans. A

Q.42 Measurement of inulin renal clearance is a measure for
(A) Effective renal blood flow (B) Renal drug excretion rate
(C) Active renal secretion (D) Glomerular filtration rate
Ans. D

Q.43 Highly branched three dimensional macromolecules with controlled structures with all bonds originating
from a central core are known as
(A) cyclodextrins (B) dextrans (C)dendrimers (D) liposomes

Q.44 Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?
(A) Sodium chloride (B) Mannitol
(C) Starch (D) HPMC

Q.45 The applicability of Noyes-Whitney equation is to describe
(A) First order kinetics (B) Zero order kinetics
(C) Mixed order kinetics (D)Dissolution rate
Ans. D

Q.46 Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid
discoloration of the tablets?
(A) Dicalcium phosphate (B) Microcrystalline cellulose
(C) Starch (D) Lactose
Ans. D

Q.47 The ability of human eye using illuminated area to detect a particle is limited to
(A) 0.4 micron (B) 25 micron (C) 50 micron (D) 10 micron

Q.48 What quantities of 95 % v/v and 45 % v/v alcohols are to be mixed to make 800 mL of 65 % v/v alcohol?
(A) 480 mL of 95 % and 320 mL of 45 % alcohol 4
(B) 320 mL of 95 % and 480 mL of 45 % alcohol
(C) 440 mL of 95 % and 360 mL of 45 % alcohol
(D)360 mL of 95 % and 440 mL of 45 % alcohol
Ans. B

Q.49 The role of borax in cold creams is
(A) anti-microbial agent
(B) to provide fine particles to polish skin
(C) in-situ emulsifier
(D) antioxidant
Ans. A

Q.50 Choose the right combination:
(A) Quinine', antimalarial, isoquinoline alkaloid
(B) Reserpine, -antihypertensive, indole alkaloid
(C) -Quantitative microscopy, stomatal number, myrrh
(D) Palmitic acid, salicylic acid , fatty acids
Ans. B

Q.51 Triterpenoids are active constituents of
(A) Jaborandi (B) Rhubarb
(C) Stramonium (D) Brahmi
Ans.D

Q.52 Alkaloids are NOT precipitated by
(A) Mayer's reagent (B) Dragendroff Reagent
(C) Picric acid (D) Millon's reagent
Ans. D

Q.53 Anisocytic stomata are present in
(A) Senna (B)Digitalis(C) Belladonna (D) Coca
Ans. C

Q.54 Bacopa monnieri plant belongs to the family
(A)Scrophulariacea (B) Leguminosae (C) Polygalaceae (D) Rubiaceae
Ans. A

Q.55 Tropane alkaloids are NOT present in
(A) Datura stramonium
(B) Erythroxylum coca
(C) Duboisia myoporoides
(D) Lobelia inflata
Ans. D

Q.56 Guggul lipids are obtained from
(A) Commiphora molmol
(B) Boswellia serrata
(C) Commiphora wightii
(D) Commiphora abyssinica
Ans. C

Q.57 An example of N-glycoside is
(A) Adenosine
(B) Sinigrin
(C) Rhein-8-glucoside
(D) Aloin
Ans. A

Q.58 One mg of Lycopodium spores used in quantitative microscopy contains an average of
(A) 94,000 spores (B) 92,000 spores (C) 90,000 spores (D) 91,000 spores
Ans. A

Q.59 Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C :
(A) Interferon with Ribavirin (B) Interferon with Zidovudine
(C) Interferon with Stavudine (D) Interferon with Lamivudine
Ans. B

Q.60 Aliskiren acts by
(A) inhibiting the conversion of Angiotensin I to II
(B) inhibiting the release of rennin
(C) inhibiting the binding of Angiotensin II to the receptor
(D) inhibiting the action of aldosterone
Ans. B

Q.61 Digitalis toxicity is enhanced by co-administration of
(A) Potassium B) Quinidine (C) Diuretics (D) Antacids
Ans. B 

Q.62 The rate limiting step in cholesterol biosynthesis is one of the followings :
(A) LDL-receptor concentration (B) VLDL secretion
(c) Mevalonic acid formation (D) Co-enzyme A formation
Ans. C

Q.63 Which one of the following drugs is withdrawn from the market due to torsade de pointes?
(A) Chlorpromazine (B) Astemizole
(C) Haloperidol (D) Domperidone
Ans. B

Q.64 Ganciclovir is mainly used for the treatment of infection caused by
(A) Cytomegalovirus (B) Candida albicans
(C) Herpes zoster virus (D) Hepatitis B virus
Ans. A

Q.65 Identify the one rational combination which has clinical benefit :
(A) Norfloxacin - Metronidazole (B) Alprazolam - Paracetamol
(C) Cisapride – Omeprazole (D)Amoxycillin - Clavulanic acid
Ans. D

Q.66 Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs :
(A) Sulphonamides (B) Macrolides
(C) Penicillins (D) Tetracyclines
Ans. A




Q.67 Amitryptyline is synthesized from the following starting material :
(A) Phthalic anhydride (B) Terephthalic acid
(C) Phthalamic acid (D) Phthalimide
Ans. B

Q.68 The common structural feature amongst the three categories of anticonvulsant drugs barbiturates,
succinimides and hydantoins is
(A) ureide (B) imidazolidinone
(C) dihydropyrimidine (D) tetrahydropyrimidine
Ans. A

Q.69 Nicotinic action of acetylcholine is blocked by the drug
(A) Atropine (B) Carvedilol
(C) Neostigmine ( D ) d-Tubocurarine
Ans. D

Q.70 Chemical nomenclature of procaine is
(A) 2-Diethylaminoethyl 4-aminobenzoate
(B) N,N-Diethyl 4-aminobenzoate
(C) 4-Aminobenzamidoethyl amine
(D) 4-Amino-2-diethylaminoethyl benzoate

Q.71 Barbiturates with substitution at the following position possess acceptable hypnotic
activity :
(A) 1,3-Disubstitution (B) 5,5-Disubstitution
(C) 1,5-Disubstitution (D) 3,3-Disubstitution
Ans. B

Q.72 Selective serotonin reuptake inhibitor is
(A) Imipramine (B) Iproniazide (C) Fluoxetin (D)Naphazoline
Ans. C

Q.73 Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system,
(A) Pyrimidine (B)Benzimidazole (C) Benzothiazole (D) Oxindole
Ans. B

Q.74 A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is
(A) Fluvastatin (B) Cerivastatin (C) Lovastatin (D) Somatostatin
Ans. C

Q.75 Cyclophosphamide as anticancer agent acts as
(A) alkylating agent before metabolism (B)alkylating agent after metabolism
(C) phosphorylating agent after metabolism (D) DNA intercalating agent
Ans. B

Q.76 Artemisinin contains the following group in its structure :
(A) an endoperoxide (B) an exoperoxide
(C) an epoxide (D) an acid hydrazide
Ans. A

Q.77 Indicate the HPLC detector that is most sensitive to change in temperature :
(A) PDA detector (B) Refractive Index detector
(C) Electrochemical detector (D) Fluorescence detector
Ans. B

Q.78 One of the following statements is NOT true :
(A) Accuracy expresses the correctness of measurement
(B) Precision represents reproducibility of measurement
(C) High degree of precision implies high degree of accuracy also
(D) High degree of accuracy implies high degree of precesion also
Ans. C

Q.79 In thiazides following substituent is essential for diuretic activity :
(A) Chloro group at position 6 (B) Methyl group at position 2
(C) Sulphamoyl group at position 7 (D) Hydrophobic group at position 3
Ans. C

Q.80 Streptomycin can NOT be given orally for treatment of tuberculosis because
(A) it gets degraded in the GIT (B) it causes severe diarrhoea
(C) it causes metallic taste in the mouth (D) it is not absorbed from the GIT
Ans. D

Q.81 In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than
(A) 350 nm (B) 200 nm (C) 300 nm (D) 250 nm
Ans. A

Q.82 Glass transition temperature is detected through
(A) X-Ray diffractometery (B) Solution calorimetery
(C) Differential scanning calorimetery (D) Thermogravimetric analysis
Ans. C

Q.83 In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their
(A) volatility (B) solubility
(C)thermal conductivity (D) polarizability
Ans. D

Q.84 Oxidative phosphorylation involves
(A) Electron transport system
(B) Substrate level phosphorylation
(C) Reaction catalyzed by succinic thiokinase in TCA cycle
(D) None of the above
Ans. A

Q.85 Coulter counter is used in determination of
(A) particle surface area (B) particle size
(C) particle volume (D)all of A, B, C
Ans. D

Q.86 Drugs following one compartment open model pharmacokinetics eliminate
(A) bi-exponentially (B) tri-exponentially
(C) non-exponentially (D) mono-exponentially
Ans. D

Q.87 The temperature condition for storage of drug products under cold temperature is given as :
(A) temperature between 8°C and 25°C (B) temperature below 20C
(C) temperature at 0°C (D) temperature between 2cC and S:C
Ans. D

Q.88 Many xenobiotics are oxidized by cytochrome P450 in order to
(A) increase their biological activity
(B) increase their disposition in lipophilic compartments of the body
(C) increase their aqueous solubility
(D) all of the above
Ans. D

Q.89 The following protein / polypeptide has a quaternary structure :
(A) cc-Chymotrypsin (B) Hemoglobin
(C) Insulin (D) Myoglobin
Ans.B

Q.90 Drugs in suspensions and semi-solid formulations always degrade by
(A) first order kinetics (B)second order kinetics
(C) zero order kinetics (D) non-linear kinetics

Q.91 In nail polish, following polymer is used as a film-former,
(A) Nitrocellulose (B) Polylactic acid
(C) Hydroxypropyl methylcellulose (D) Cellulose acetate phthalate
Ans. A

Q.92 Rabies vaccine (living) is prepared using
(A) Sheep blood (B) Mice lymph
(C) Horse plasma (D) Fertile eggs

Q.93 A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is,
(A) 125% (B) 250 % (C) 12.5% (D) 1.25%
Ans.C

Q.94 Geriatric population should be included in the following Phase of clinical trials
(A) Phase I (B) Phase II (C) Phase III (D) Phase IV
Ans. C

Q.95 Class 100 area is referred to
(A) Manufacturing area (B) Aseptic area
(C) Clean room (D) Ware house
Ans. B

Q.96 How many mL of a 1:500 w/v stock solution should be used to make 5 liters of 1:2000 w/v solution?
(A) 750 mL (B) 1000 mL (c) 1250 mL (D) 1500 mL
Ans. C

Q.97 The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL
instantaneous concentration in plasma shall be
(A)10 L (B) 100 L (C) 1.0 L (D) 0.10 L
Ans. A

Q.98 It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be
(A) 600 mg (B) 300 mg 30 mg (D) 60 mg

Q.99 Which one of the following is NOT an ex-officio member of Pharmacy Council of India?
(A) The Director General of Health Services
(B) The Director of Central Drugs Laboratory
(C) The Drugs Controller General of India
(D) The Director of Pharmacopoeia Laboratory
Ans. D

Q.100 In which of the following techniques the sample is kept below triple point?
(A) Lyophilization (B) Spray drying
(C) Spray congealing (D) Centrifugation
Ans. A

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प्रेम कुणावरही करू नये Dont fall In Love Marathi Poem

Dont fall In Love Marathi Poem

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